Purpose & Scope:
SVP PFL provides leadership and strategic direction for research, development, manufacturing, and commercialization of the Primary Focus pipeline globally. SVP PFL manages complex portfolio of including 20+ research and development stage projects and 4+ modality platforms. SVP PFL determines extension of PF, resource allocation and pipeline priorities, leads execution and accountable for related budget. SVP PFL chairs PFIO LT and collaborates with the relevant Divisions to achieve PF goals.
Essential Job Responsibilities:
•Create and revise PF Strategy to define the direction, capability and resource need of the diverse PF modalities and pipeline (EC)
•Create the PF Roadmap to define execution plan and consolidated PF budget
•Update strategy and roadmap driven by the rapidly changing scientific and competitive environment
•Chairs PFIO LT, lead representatives of relevant functions to develop PF Strategy and implement the Roadmap, and guide Asset Teams
and Research functions
•Motivates and creates unique culture to drive high performance
•Drives continuous investment into the PF, on order to evolve it and maximize its value
•Monitors and reports progress of projects in each PF per Roadmap
•Define the PF Business Development strategy to evolve Primary Focus. Collaborates with BD and CS to evaluate external assets and
drives decision in Corporate Governance
•Endorse project team’s proposal at KC
•Creates PF budget and accountable for budget spending through Functional Units
•Represents Astellas in committees and external scientific/industry forums
Scope:
•Employee Headcount in matrix team: 150+ FTE in 5+ Divisions
•Estimated Operating Budget: $250M R&D budget, PFL is accountable for planning and execution
•Future revenue impact is significant
•Global scope, impacts several divisions and /broad pipeline in multiple research and development stages
•Other: strategy and milestone decisions impact overall value of Astellas pipeline and valuation
Key Relationships:
•Reports to CSTO
•Leadership Roles: Core member of KC (portfolio governance). Chair of the PFIO LT. Chair of Joint Steering Committees of external research collaborations
•Executive Committee and other Governance Committee members
•President of IO, Xyphos, UCELL, IRM, SVP of Development, Early Dev, Regulatory, BD, CS, Finance, Commercial, Market Access
•CEO/CBO/CSO of partner biotech (Cytomx, Kalivir, Kelonia, etc.), other PFLs
•Leaders of external companies related to BD and research activities
•Key External Experts, Scientific Advisory Board Members
•Represents Astellas IO in investor, business, scientific community
Required Qualifications:
•Master's degree. MD, PhD, or PharmD preferred.
•15-20 y experience in cancer drug development in pharma industry
•Capability to develop strategy and solutions for unprecedented, novel business areas
•Capable of setting direction of complex matrix organization
•Inspirational, collaborator both externally and internally